Autophagy in non-alcoholic fatty liver disease and alcoholic liver disease
نویسندگان
چکیده
منابع مشابه
Autophagy and Non-Alcoholic Fatty Liver Disease
Autophagy, or cellular self-digestion, is a catabolic process that targets cell constituents including damaged organelles, unfolded proteins, and intracellular pathogens to lysosomes for degradation. Autophagy is crucial for development, differentiation, survival, and homeostasis. Important links between the regulation of autophagy and liver complications associated with obesity, non-alcoholic ...
متن کاملClinical Manifestations and Diagnosis of Non-Alcoholic Fatty Liver Disease
Background & Objective: Nonalcoholic fatty liver diseases (NAFLD) is the major cause of hepatocellular carcinoma and increases the risk of mortality. Understanding the trends of its clinical and biochemical changes is essential to identify patients with NAFLD that are at the greatest risk of nonalcoholic steatohepatitis (NASH) and cirrhosis in Iran. M...
متن کاملNon-alcoholic Fatty Liver Disease
Non-alcoholic fatty liver disease describes a range of conditions caused by a build-up of fat within liver cells. It is very common and in many cases is linked to being obese or overweight. Most people with non-alcoholic fatty liver disease do not develop serious liver problems. In some people, the build-up of fat in the liver can lead to serious liver disease. However, all people with non-alco...
متن کاملNon-Alcoholic Fatty Liver Disease
Results: The term “non-alcoholic fatty liver disease” covers cases of a wide spectrum of severity, ranging from bland fatty liver without any inflammation and with little or no tendency to progress all the way to non-alcoholic steato hepatitis (NASH) with inflammatory reactions and hepatocyte damage, with or without fibrosis. Some 5% to 20% of patients with NAFLD develop NASH, which undergoes a...
متن کاملNon-alcoholic Fatty Liver Disease
Non-alcoholic fatty liver disease describes a range of conditions caused by a build-up of fat within liver cells. It is very common and in many cases is linked to being obese or overweight. Most people with non-alcoholic fatty liver disease do not develop serious liver problems. In some people, the build-up of fat in the liver can lead to serious liver disease. However, all people with non-alco...
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ژورنال
عنوان ژورنال: Liver Research
سال: 2018
ISSN: 2542-5684
DOI: 10.1016/j.livres.2018.09.004